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A rental car stopped on a road in Greater Kruger area on our best South Africa self-drive itinerary as an elephant crosses.
Private Self-Drive Tour

South Africa Highlights

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South Africa Highlights - 21-Day Best South Africa Self-Drive Itinerary

This is the best South Africa self-drive itinerary – from Johannesburg to Cape Town, combining spectacular landscapes, wildlife and coastal experiences.

Travel through the Panorama Route to the Greater Kruger for unforgettable game drives, then continue through Eswatini to St Lucia and Durban.

From Durban, fly to Port Elizabeth and follow the Garden Route to Cape Town via Knysna, Oudtshoorn, Hermanus and the Cape Winelands.

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Any day of your choice

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Highlights

Day 1 to 21 | South Africa

Visit the Union Buildings, Voortrekker Monument Museum, and enjoy delicious food.

Pretoria

Visit the Union Buildings, Voortrekker Monument Museum, and enjoy delicious food.

Explore spectacular landscapes, including Blyde River Canyon, God’s Window and Bourke’s Luck Potholes.

Panorama Route

Explore spectacular landscapes, including Blyde River Canyon, God’s Window and Bourke’s Luck Potholes.

Enjoy game drives in the Klaserie Private Nature Reserve and search for the Big Five.

Greater Kruger
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Enjoy game drives in the Klaserie Private Nature Reserve and search for the Big Five.

Explore the Ezulwini Valley, visit Mlilwane Wildlife Sanctuary, and discover local crafts.

Eswatini (Swaziland)

Explore the Ezulwini Valley, visit Mlilwane Wildlife Sanctuary, and discover local crafts.

Cruise the St Lucia Estuary, explore iSimangaliso Wetland Park, and enjoy the beach.

St Lucia

Cruise the St Lucia Estuary, explore iSimangaliso Wetland Park, and enjoy the beach.

Visit the spice market, uShaka Marine World, the Botanic Gardens, and the Muthi Market.

Durban

Visit the spice market, uShaka Marine World, the Botanic Gardens, and the Muthi Market.

Enjoy the coast with opportunities for surfing, kayaking, boat trips, and beach time.

St Francis Bay

Enjoy the coast with opportunities for surfing, kayaking, boat trips, and beach time.

Visit Tsitsikamma National Park, explore the Knysna Heads, and enjoy the lagoon.

Knysna
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Visit Tsitsikamma National Park, explore the Knysna Heads, and enjoy the lagoon.

Visit an ostrich farm, explore the Cango Caves, or drive the Swartberg Pass.

Oudtshoorn
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Visit an ostrich farm, explore the Cango Caves, or drive the Swartberg Pass.

Watch for whales in Walker Bay or hike along the rugged coastline.

Hermanus
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Watch for whales in Walker Bay or hike along the rugged coastline.

Explore the city, visit the V&A Waterfront, or hike Table Mountain or Lion’s Head.

Cape Town
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Explore the city, visit the V&A Waterfront, or hike Table Mountain or Lion’s Head.

Explore the historic town and surrounding vineyards, with opportunities for wine tasting.

Stellenbosch
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Explore the historic town and surrounding vineyards, with opportunities for wine tasting.

Who Should Go

This is the best South Africa self-drive itinerary for those who want to see as much as possible while enjoying the freedom of travelling by car.

It’s also well suited to first-time self-drivers. You’ll travel mainly on well-maintained roads, with no need for off-road driving or bush mechanic experience.

If you like to plan ahead but don’t have the time, we’ll arrange your accommodation and vehicle so you can focus on enjoying the journey.

The tour is perfect for those who enjoy nature, wildlife, culture and outdoor experiences, from scenic drives and game drives to hiking, boating, swimming, snorkelling and relaxing on the beach.

  • Independent Travellers
  • Couples
  • South Africa Newbies
  • Confident Drivers
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Independent Travellers

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Couples

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South Africa Newbies

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Confident Drivers

'I would like to thank you for your friendly and competent consulting with regards to the booking of our self-drive tour “South Africa Highlights”. Right from the beginning, we felt in good hands and were not disappointed.’
Alexandra Keppeler and family | Self-Drive Tour

Accommodation

13 accommodations over 21 days/20 nights
Cosy bedroom interior at Brooks Cottage.
Day 1
Pretoria
Brooks Cottage
1 night bed & breakfast
Day 1
Thatched-roof bungalows at Xanatseni Private Camp
Day 4-5
Greater Kruger Park
Xanatseni Private Camp
2 nights full-board
Day 4-5
Elegant dining room with floral chairs and wooden beam ceiling at Nut Grove Manor.
Day 6
White River
Nut Grove Boutique Hotel
1 night half-board
Day 6
A double room at Mogi Boutique Hotel with tropical decor, floral cushions and French doors opening onto a garden.
Day 7
Eswatini
Mogi Boutique Hotel
1 night bed & breakfast
Day 7
A double room at St Lucia Wetlands Guesthouse with a four-poster bed, wooden ceiling and hardwood floors.
Day 8-9
St Lucia
St Lucia Wetlands Guesthouse
2 nights bed & breakfast
Day 8-9
Fairlight Beach House terrace with seating overlooking the Indian Ocean at sunset.
Day 10
Umdloti
Fairlight Beach House
1 night bed & breakfast
Day 10
Pool at Bonbini Guest House
Day 11-12
St. Francis Bay
Bonbini Guest House
2 nights bed & breakfast
Day 11-12
Aerial view of Stannards Guesthouse surrounded by lush gardens with a swimming pool and spacious lawn.
Day 13-14
Knysna
Stannards Guest Lodge
2 nights bed & breakfast
Day 13-14
Interior of a spacious double bedroom at Thabile Lodge.
Day 15
Oudtshoorn
Thabile Lodge
1 night half-board
Day 15
Bamboo Guest House pool and garden with sun loungers, wooden deck and lush greenery under a blue sky.
Day 16
Hermanus
Bamboo Guest House
1 night bed & breakfast
Day 16
A double bed at Rosedene Guesthouse in Cape Town
Day 17-18
Cape Town
Rosedene Guest House
2 nights bed & breakfast
Day 17-18

Tour Itinerary

Self-Drive Tour South Africa

The best South Africa self-drive itinerary begins in Johannesburg and concludes in Cape Town.

Fly to Johannesburg, collect your vehicle and travel to Pretoria before continuing along the scenic Panorama Route to the Greater Kruger, where you’ll enjoy game drives in the Klaserie Private Nature Reserve.

Continue through Eswatini to St Lucia and the Indian Ocean, with wildlife experiences in iSimangaliso Wetland Park and Hluhluwe-iMfolozi Park, before flying from Durban to Port Elizabeth.

From there, follow the Garden Route through St Francis Bay, Knysna and Oudtshoorn to Hermanus, before ending in Cape Town and the Capes Winelands.

South Africa Highlights map

Start Johannesburg

Ends Cape Town

Close-up of a white Water Lily.

Day 1 | Johannesburg – Pretoria

Distance approx. 50 km; driving time approx. ½-1 hour

Johannesburg – Pretoria

Distance approx. 50 km; driving time approx. ½-1 hour

Upon arrival at OR Tambo Airport, you pick up your rental car and make your way to Brooks Cottage in Pretoria — the first stop on the best South Africa self-drive itinerary.

The rest of the day is yours to spend at leisure. You may choose to explore Pretoria or simply relax at the guesthouse and take a refreshing dip in the pool. Shops and restaurants are within walking distance.

River stream surrounded by green bush nearby the Blyde River Canyon.

Day 2 - 3 | Pretoria – Graskop

Distance day 2: approx. 370 km; driving time approx. 5 hours

Pretoria – Graskop

Distance day 2: approx. 370 km; driving time approx. 5 hours

After breakfast you head in an easterly direction through the provinces of Gauteng and Mpumalanga. Along the way you pass the towns of eMalaheni and Mashishing (formerly Lydenburg) before heading to Pilgrims Rest. Take a moment to browse through this small historical town and travel back to the days of the gold rush. In the afternoon, you continue to the Graskop Hotel, your accommodation for the following two nights.

Depending on your time of arrival you can visit the nearby Graskop Gorge Lift. Enjoy the beautiful views and take the lift down into the gorge where walkways and suspension bridges meander through indigenous forest.

You have the whole next day to explore the breathtaking Panorama Route. Visit the Blyde River Canyon, God’s Window and Bourke’s Luck Potholes. If you haven’t had a chance to visit the Graskop Lift the previous day, don’t miss it today.

Breakfast Dinner
Close-up of the head of a curious leopard in the Kruger National Park.

Day 4 - 5 | Graskop – Klaserie Private Nature Reserve, Greater Kruger Park

Distance day 4: approx. 140 km; driving time approx. 2-3 h

Graskop – Klaserie Private Nature Reserve, Greater Kruger Park

Distance day 4: approx. 140 km; driving time approx. 2-3 h

Look forward to three amazing days of wildlife viewing in !

Today, you leave the Panorama Route behind and travel to the 60,000-hectare Klaserie Private Nature Reserve, which forms part of the Greater Kruger area and shares an unfenced boundary with Kruger National Park. Wildlife moves freely between the different reserves, creating excellent opportunities for memorable sightings in a quieter and more exclusive setting.

During your two-night stay, you head out on morning and afternoon game drives in an open safari vehicle, accompanied by an experienced ranger. The reserve is home to an impressive variety of wildlife, including the Big Five – lion, leopard, buffalo, rhino and elephant – as well as many other species.

Between game drives, enjoy the meals served at the lodge, cool off in the swimming pool, work out at the gym or watch for wildlife from the lookout tower overlooking the waterhole in front of the camp.

The intimate Xanatseni Private Camp is your home for the next two nights in the bush.

 

Breakfast Lunch Dinner
Martial Eagle sitting on a dead branch.

Day 6 | Greater Kruger Park – White River

Distance approx. 180 km; driving time approx. 3-4 h

Greater Kruger Park – White River

Distance approx. 180 km; driving time approx. 3-4 h

Start the day with a final morning game drive in the Klaserie Private Nature Reserve. No two game drives are ever quite the same, so keep your eyes open for wildlife you may not have encountered during the previous days.

In the late morning, you leave the bush behind and make your way to the beautiful Nut Grove Boutique Hotel, situated just outside White River. Spend a leisurely afternoon in the hotel’s gardens, relax by the swimming pool or indulge in a treatment at the in-house spa.

You spend the night in one of the Luxury Suites at Nut Grove Boutique Hotel.

Breakfast Dinner
Scenic view of a valley and mountains, ideal for a South Africa self-drive itinerary.

Day 7 | White River – Ezulwini Valley, Eswatini

Distance approx. 230 km; driving time approx. 4 hours

White River – Ezulwini Valley, Eswatini

Distance approx. 230 km; driving time approx. 4 hours

Today, you cross the border into Eswatini and continue towards the Ezulwini Valley. Along the way, stop at the colourful market in Mbabane, where you can browse a variety of local produce and handicrafts.

The Ezulwini Valley, also known as the “Valley of Heaven”, and its surrounding mountains offer plenty of activities. You can go hiking, cycling or horse riding at Mlilwane Wildlife Sanctuary, visit Mantenga Cultural Village or stop at the nearby Swazi Candles factory to see the decorative candles being made by hand.

The night is spent at Mogi Boutique Hotel in the Ezulwini Valley.

Breakfast
Orange sunset on St Lucia lake.

Day 8 | Ezulwini Valley, Eswatini – St Lucia

Distance approx. 340 km; driving time approx. 5 hours

Ezulwini Valley, Eswatini – St Lucia

Distance approx. 340 km; driving time approx. 5 hours

Re-entering South Africa at the Lavumisa border post, you reach the province of KwaZulu-Natal and continue to the town of St Lucia, situated on the edge of iSimangaliso Wetland Park.

St Lucia offers a variety of activities. Join a boat cruise on the St Lucia Estuary to see hippos and crocodiles, explore the surrounding forests on foot or spend some time relaxing on the beach. You can also drive through iSimangaliso Wetland Park to Cape Vidal, where you can swim and snorkel in the rock pools, or book a guided game drive in the park. The area is also a birdwatcher’s paradise, with hundreds of species to look out for.

Your accommodation for tonight is St Lucia Wetlands Guesthouse.

Breakfast
Close-up on an elephants skin texture and small tusks.

Day 9 | St Lucia – Hluhluwe-iMfolozi Park – St Lucia

Distance approx. 100 km; driving time approx. 2 hours (excl. game drives)

St Lucia – Hluhluwe-iMfolozi Park – St Lucia

Distance approx. 100 km; driving time approx. 2 hours (excl. game drives)

An early start awaits you today as you head to Hluhluwe-iMfolozi Park for a full day of wildlife viewing. A short drive past sugar cane plantations and forests takes you to this renowned Big Five reserve.

Hluhluwe-iMfolozi is particularly well known for its rhino conservation efforts and is home to both black and white rhinos. Also keep your eyes open for the other members of the Big Five as well as the many other animals found in the park.

In the late afternoon, you return to St Lucia Wetlands Guesthouse for a second night.

Breakfast
Colorful African fabrics on Durban local maket

Day 10 | St Lucia – Durban

Distance approx. 270 km; driving time approx. 3-4 hours

St Lucia – Durban

Distance approx. 270 km; driving time approx. 3-4 hours

Today, your journey takes you to Durban, one of the busiest trading centres on the Indian Ocean. The city is home to South Africa’s largest Indian community, which contributes to its vibrant and multicultural character. Visit the colourful Victoria Street Market and browse its stalls filled with spices, crafts and souvenirs, or enjoy a stroll along the famous Golden Mile beachfront. Another popular attraction is uShaka Marine World with its impressive aquarium.

In the afternoon, continue to Umdloti, around 19 km north of Durban. Fairlight Beach House is situated right on the beachfront, making it the perfect place to relax by the ocean before enjoying dinner at one of the nearby restaurants.

Breakfast
Long straight highway through South Africa's landscape with mountains in the background.

Day 11 - 12 | Durban – Port Elizabeth Airport – St. Francis Bay

Distance to King Shaka Airport: approx. 10 km; driving time approx. ½ hour
Distance to St. Francis Bay: approx. 120 km; driving time approx. 1-2 hours

Durban – Port Elizabeth Airport – St. Francis Bay

Distance to King Shaka Airport: approx. 10 km; driving time approx. ½ hour
Distance to St. Francis Bay: approx. 120 km; driving time approx. 1-2 hours

After breakfast, you make your way to Durban’s King Shaka International Airport, return your rental car and board your flight to Port Elizabeth. Upon arrival, you pick up another rental car and continue via Humansdorp to the seaside village of St Francis Bay.

The rest of the afternoon and the following day are yours to spend at leisure. Go surfing, snorkelling or sea kayaking, join a boat cruise, play a round of golf, stretch your legs on a walk in one of the nearby nature reserves or simply relax on the beach.

You spend two nights at the cosy BonBini Guest House.

Breakfast
Tsitsikamma suspension brige at Storms River.

Day 13- 14 | St. Francis Bay – Knysna

Distance day 13: approx. 190 km; driving time approx. 3 hours

St. Francis Bay – Knysna

Distance day 13: approx. 190 km; driving time approx. 3 hours

Leaving St Francis Bay behind, your journey continues along the famous Garden Route. On the way, stop at Tsitsikamma National Park, known for its indigenous forests and dramatic coastline.

Put on your walking shoes and explore one of the park’s scenic hiking trails before continuing via the seaside town of Plettenberg Bay to Knysna, well known for its lagoon, oyster farming and timber industry. Spend the next day exploring Knysna and its surroundings. Drive up to one of the viewpoints at the Knysna Heads, take a boat trip on the lagoon, go swimming or discover the surrounding forests on foot or by bicycle.

Stannards Guest Lodge is your home for the next two nights.

Breakfast
Interior of the Cango Caves on Route 62.

Day 15 | Knysna – Oudtshoorn

Distance approx. 150 km; driving time approx. 2-3 hours

Knysna – Oudtshoorn

Distance approx. 150 km; driving time approx. 2-3 hours

Your journey takes you through George and over the scenic Outeniqua Pass to Oudtshoorn in the Little Karoo. The town is well known for its ostrich farms and the impressive Cango Caves, where you can explore a fascinating network of underground chambers and passages.

If you are looking for a little more adventure, take a drive up the spectacular Swartberg Pass and enjoy the views across the surrounding mountains and valleys.

For tonight, you stay at Thabile Lodge in the countryside outside Oudtshoorn.

 

Breakfast Dinner
Two men on a coastal hike along the Garden Route.

Day 16 | Oudtshoorn – Hermanus

Distance approx. 380 km; driving time approx. 5-6 hours

Oudtshoorn – Hermanus

Distance approx. 380 km; driving time approx. 5-6 hours

Following the scenic R62, you pass through the towns of Calitzdorp, Ladismith and Montagu before continuing via Swellendam to Hermanus on the shores of Walker Bay. Between June and November, southern right whales visit the bay to breed, offering excellent opportunities to spot them from the shore. Keep an eye on the ocean as you explore the town and its coastline.

Outside of whale season, the area is equally worth exploring, with beautiful walks along the rugged coast or through the nearby forests.

Your accommodation for tonight is the Bamboo Guest House in Hermanus.

Breakfast
Small group on a hike towards Lion's Head.

Day 17 - 18 | Hermanus – Cape Town

Distance day 17: approx. 140 km; driving time approx. 2-3 hours

Hermanus – Cape Town

Distance day 17: approx. 140 km; driving time approx. 2-3 hours

After breakfast, you travel to the Mother City, Cape Town. Set between Table Mountain and the Atlantic Ocean, Cape Town enjoys one of the most spectacular settings in the world and offers plenty to see and do.

Explore the city centre and colourful Bo-Kaap, browse the shops, restaurants and markets at the V&A Waterfront or visit Kirstenbosch National Botanical Garden on the slopes of Table Mountain. Weather permitting, take the cableway to the top of Table Mountain for magnificent views across the city and surrounding coastline.

If you prefer something more active, hike up Table Mountain or Lion’s Head, or enjoy a walk along the Sea Point promenade. You can also relax on the beaches of Camps Bay or Clifton or take the ferry to historic Robben Island.

Rosedene Guest House will be your base for the next two nights.

Breakfast
Cape point rugged coastline landscape.

Day 19 - 20 | Cape Town – Stellenbosch

Distance day 19: approx. 160 km; driving time approx. 4-5 hours (incl. Cape of Good Hope)

Cape Town – Stellenbosch

Distance day 19: approx. 160 km; driving time approx. 4-5 hours (incl. Cape of Good Hope)

Start the day early and set off to explore the Cape Peninsula. Follow the spectacular Chapman’s Peak Drive to Cape Point and the Cape of Good Hope, with beautiful views of the coastline and Atlantic Ocean along the way. From here, continue to Boulders Beach near Simon’s Town, home to a colony of African penguins, before travelling via Fish Hoek and Muizenberg to Stellenbosch in the heart of the Cape Winelands.

Surrounded by mountains and vineyards, Stellenbosch is well worth exploring on foot, with its historic streets and beautiful Cape Dutch architecture. Visit some of the surrounding wine estates for a tasting or enjoy a hike in the nearby Jonkershoek Nature Reserve.

For the final two nights of your journey, you stay at Bonne Esperance Guest House, centrally located in Stellenbosch.

 

You continue your trip via Simon’s Town, Fish Hoek and Muizenberg to Stellenbosch in the heart of the . The surrounding mountains create a dramatic

Breakfast

Day 21 | Stellenbosch – Cape Town Airport

Distance approx. 40 km; driving time approx. 1 hour

Stellenbosch – Cape Town Airport

Distance approx. 40 km; driving time approx. 1 hour

Enjoy a final leisurely breakfast at your guesthouse and perhaps do some last-minute souvenir shopping before making your way to Cape Town International Airport. Here, you return your rental car and check in for your flight home, bringing the best South Africa self-drive itinerary to an end.

Should you wish to extend your stay in the Cape or combine this journey with another trip through Southern Africa, we will gladly assist you with the arrangements.

Breakfast

Included

  • 20 nights’ stay in guesthouses and lodges (depending on availability, accommodation of a similar standard will be booked)
  • meals according to the itinerary
  • two scheduled game drives daily at Xanatseni Private Camp
  • domestic flight from Durban to Port Elizabeth in economy class

Excluded

  • additional flights (domestic and international)
  • rental car (please contact us for a quote)
  • fuel
  • possible toll and crossing border fees
  • meals not indicated in the itinerary
  • alcoholic and soft drinks
  • national park fees
  • optional activities
  • tips
  • personal expenses
  • visa fees
  • travel insurance

Upcoming Departures

If you prefer different dates or have any questions, please get in touch - we are happy to help!
All tour prices are charged in ZAR. The displayed rates are converted for reference only.
Season per person sharing per person single room per person triple room Children < 12 (with extra bed)
01.09.2026-
31.10.2026
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01.11.2026-
13.12.2026
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14.12.2026-
31.12.2026
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01.01.2027-
10.01.2027
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11.01.2027-
31.03.2027
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01.04.2027-
30.04.2027
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01.05.2027-
30.09.2027
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01.10.2027-
31.10.2027
getting current exchange rate... getting current exchange rate... on request on request
01.11.2027-
12.12.2027
getting current exchange rate... getting current exchange rate... on request on request
13.12.2027-
31.12.2027
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Viewpoint high above Blyde River Canyon, South Africa.

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All tour prices are charged in ZAR. The displayed rates are converted for reference only.